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What biochemical tests are used to diagnose this?


Alpha-human chorionic gonadotropin (hCG) hormone levels is the main test of ectopic pregnancy. Human chorionic gonadotropin levels become detectable when there is a pregnancy. This can be detected through urine or blood. In ectopic pregnancies, the fertilized egg is unable to create beta-hCG. Therefore only the alpha is used for detection. In ectopic pregnancy the levels of hCG detectable are quite small because the implantation did not occur in the uterus. The technique used to detect the alpha-hCG levels must be quite precise. Other tests used are detection of different trophoblast glycoproteins such as Schwangerschaftsprotein 1 and pregnancy-associated plasma protein A, oestradiol levels, endometrial and decidual proteins, the fetal protein alphafetoprotein, and the enzymes rennin and amylase (Stabile, 1996).

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